EZH2 antibody

Catalog No. ABIN6937201

Product Details anti-EZH2 Antibody

Target: EZH2 (Enhancer of Zeste Homolog 2 (EZH2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This EZH2 antibody is un-conjugated

Application: Western Blotting (WB)

Specificity: This gene encodes a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein associates with the embryonic ectoderm development protein, the VAV1 oncoprotein, and the X-linked nuclear protein. This protein may play a role in the hematopoietic and central nervous systems. Multiple alternatively splcied transcript variants encoding distinct isoforms have been identified for this gene.

Cross-Reactivity (Details): Human.

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogen: Recombinant full-length human EZH2 protein

Clone: EZH2-2536

Isotype: IgG2a kappa

Application Details

Application Notes:

Known_Application: Western Blot (1-2 μg/mL), Optimal dilution for a specific application should be determined.

Positive_Control: MCF7, HeLa, U-2 OS or HEK-293 whole cell lysates. Human tonsil, testis or prostate tissue.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Preservative: Azide free

Storage: -20 °C,-80 °C

Storage Comment: Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Expiry Date: 24 months

Target Details for EZH2

Target: EZH2 (Enhancer of Zeste Homolog 2 (EZH2))

Alternative Name: EZH2 (EZH2 Products)

Synonyms: ENX-1 antibody, ENX1 antibody, EZH1 antibody, EZH2b antibody, KMT6 antibody, KMT6A antibody, WVS antibody, WVS2 antibody, eya2 antibody, im:7149338 antibody, zgc:136376 antibody, zgc:152758 antibody, EZH2 antibody, enx-1 antibody, enx1 antibody, ezh1 antibody, kmt6 antibody, xez antibody, Enx-1 antibody, Enx1h antibody, mKIAA4065 antibody, ezh2 antibody, olezh2 antibody, enhancer of zeste 2 polycomb repressive complex 2 subunit antibody, enhancer of zeste 2 polycomb repressive complex 2 subunit L homeolog antibody, enhancer of zeste 2 polycomb repressive complex 2 subunit S homeolog antibody, EZH2 antibody, ezh2 antibody, Ezh2 antibody, ezh2.L antibody, ezh2.S antibody

Background: Enhancer of zeste 2 polycomb repressive complex 2 subunit, Enhancer of zeste homolog 2 (EZH2), ENX1, Enx1h, EZH2b, Histone-lysine N-methyltransferase EZH2, KMT6, KMT6A, Lysine N-methyltransferase 6, WVS, WVS2,EZH2 / KMT6
Cellular localisation: Nucleus.

Molecular Weight: 81-102kDa

Gene ID: 2146, 444082

UniProt: Q15910

Pathways: Retinoic Acid Receptor Signaling Pathway, Regulation of Muscle Cell Differentiation