FABP2 antibody

Catalog No. ABIN6937208

This Mouse Monoclonal antibody specifically detects FABP2 in IHC (f). It exhibits reactivity toward Human.

Quick Overview for FABP2 antibody (ABIN6937208)

Target: FABP2 (Fatty Acid Binding Protein 2, Intestinal (FABP2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This FABP2 antibody is un-conjugated

Application: Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

Clone: CPTC-FABP2-3

Product Details anti-FABP2 Antibody

Specificity: The intracellular fatty acid-binding proteins (FABPs) belong to a multigene family with nearly twenty identified members. FABPs are divided into at least three distinct types, namely the hepatic-, intestinal- and cardiac-type. They form 14-15 kDa proteins and are thought to participate in the uptake, intracellular metabolism and/or transport of long-chain fatty acids. They may also be responsible in the modulation of cell growth and proliferation. Intestinal fatty acid-binding protein 2 gene contains four exons and is an abundant cytosolic protein in small intestine epithelial cells. This gene has a polymorphism at codon 54 that identified an alanine-encoding allele and a threonine-encoding allele. Thr-54 protein is associated with increased fat oxidation and insulin resistance.

Cross-Reactivity (Details): Human.

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogen: Recombinant full length human FABP2 protein

Isotype: IgG1 kappa

Application Details

Application Notes:

Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

Positive_Control: MOLT-4 or HEK-293 cell lines. Esophagus, Skin. Keratinocytes, highly expressed in psoriatic skin. Colon.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Preservative: Azide free

Storage: -20 °C,-80 °C

Storage Comment: Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Expiry Date: 24 months

Target Details for FABP2

Target: FABP2 (Fatty Acid Binding Protein 2, Intestinal (FABP2))

Alternative Name: FABP2

Background: FABPI, I-FABP, MGC133132, Fatty Acid-Binding Protein, Intestinal,FABP2 (Marker of Metastatic Potential in Colorectal Cancer)
Cellular localisation: Cytoplasmic

Molecular Weight: 15.21kDa

Gene ID: 2169, 282265

UniProt: P12104