HHV8 antibody

Catalog No. ABIN6937460

This Rat Monoclonal antibody specifically detects HHV8 in IHC, ELISA, Coat, IF and StM. It exhibits reactivity toward Herpes Simplex Virus (HSV).

Quick Overview for HHV8 antibody (ABIN6937460)

Target: HHV8 (Herpes Virus Type 8 (HHV8))

Reactivity: Herpes Simplex Virus (HSV)

Host: Rat

Clonality: Monoclonal

Conjugate: This HHV8 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA, Coating (Coat), Immunofluorescence (IF), Staining Methods (StM)

Clone: LN53

Product Details anti-HHV8 Antibody

Purification: Purified by Protein A/G

Immunogen: Recombinant protein corresponding to the latent nuclear antigen 1 molecule of HHV8

Isotype: IgG2c kappa

Application Details

Application Notes:

Positive Control: Herpes simplex type 1 (HSV-1) extract or infected cells. Tissue.

Known Application: ELISA (For coating use Ab at 1-5 μg/mL, order Ab without BSA), Immunofluorescence (1-2 μg/mL), Immunohistochemistry (Formalin-fixed) (0.5-1 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Tris buffer with 1 mM EDTA, pH 9.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Handling

Buffer: 10 mM PBS without BSA and without Azide.

Preservative: Azide free

Storage: 4 °C,-80 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months.

Expiry Date: 24 months

Target Details for HHV8

Target: HHV8 (Herpes Virus Type 8 (HHV8))

Alternative Name: Human Herpes Virus 8 (HHV8)

Target Type: Virus

Background: HHV 8 encodes a latent nuclear antigen (LNA), which is the product of the viral gene orf 73. LNA is capable of forming a complex with retinoblastoma susceptibility gene product, which may be related to its oncogenic activity. HHV8 is associated with three different diseases observed in AIDS patients, kaposi's sarcoma, primary effusion lymphoma (which is a rare type of non-Hodgkin lymphoma affecting the body cavities) and multicentric Castleman's disease. HHV 8 is the likely etiological agent of Kaposis sarcoma.