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PMEPA1 antibody

PMEPA1 Reactivity: Human IHC, IHC (f) Host: Mouse Monoclonal PMEPA1-2696 unconjugated
Catalog No. ABIN6938198
  • Target See all PMEPA1 Antibodies
    PMEPA1 (Prostate Transmembrane Protein, Androgen Induced 1 (PMEPA1))
    Reactivity
    • 19
    • 3
    • 2
    Human
    Host
    • 13
    • 6
    Mouse
    Clonality
    • 12
    • 7
    Monoclonal
    Conjugate
    • 17
    • 1
    • 1
    This PMEPA1 antibody is un-conjugated
    Application
    • 13
    • 11
    • 7
    • 5
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
    Specificity
    PMEPA1 (prostate transmembrane protein, androgen induced 1 is a 287 amino acid single-pass membrane protein that contains WW-binding motifs and localizes to the cell membrane. Expressed at high levels in prostate, kidney and ovary, PMEPA1 interacts with NEDD4 and may play a role in regulating AR (androgen receptor) levels, specifically in prostate cells. Down regulation of PMEPA1 is observed in prostate tumors, suggesting that PMEPA1 may exhibit activity as a tumor suppressor. Overexpression of this protein may play a role in multiple types of cancer.
    Cross-Reactivity (Details)
    Human.
    Purification
    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
    Immunogen
    Recombinant full-length human PMEPA1 protein
    Clone
    PMEPA1-2696
    Isotype
    IgG1 kappa
    Top Product
    Discover our top product PMEPA1 Primary Antibody
  • Application Notes

    Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

    Positive_Control: Human prostate, breast or renal cell carcinoma tissue (IHC).

    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    Prepared in 10 mM PBS, WITHOUT BSA and Azide.
    Preservative
    Azide free
    Storage
    -20 °C,-80 °C
    Storage Comment
    Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
    Expiry Date
    24 months
  • Target
    PMEPA1 (Prostate Transmembrane Protein, Androgen Induced 1 (PMEPA1))
    Alternative Name
    PMEPA1 (PMEPA1 Products)
    Synonyms
    Tmepai antibody, PMEPA1 antibody, TMEPAI antibody, zgc:92731 antibody, tmepai antibody, STAG1 antibody, 2210418I02Rik antibody, AW455466 antibody, Erg1.2 antibody, N4wbp4 antibody, Stag1 antibody, prostate transmembrane protein, androgen induced 1 antibody, prostate transmembrane protein, androgen induced 1 L homeolog antibody, Pmepa1 antibody, PMEPA1 antibody, pmepa1 antibody, pmepa1.L antibody
    Background
    PMEPA, PMEPA1, Prostate transmembrane protein, androgen induced 1, Solid tumor-associated 1 protein, STAG1, TMEPAI, Transmembrane prostate androgen-induced protein, Transmembrane, prostate androgen induced RNA,PMEPA1 / TMEPAI (Tumor Suppressor Oncoprotein)
    Cellular localisation: Cell surface. Cytoplasm.
    Molecular Weight
    32kDa
    Gene ID
    56937, 517155
    Pathways
    Intracellular Steroid Hormone Receptor Signaling Pathway
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