UCHL1 antibody

Catalog No. ABIN6938726

This Mouse Monoclonal antibody specifically detects UCHL1 in WB. It exhibits reactivity toward Human, Rat, Mouse, Cow, Pig, Guinea Pig, Rabbit, Dog, Zebrafish (Danio rerio) and Sheep.

Quick Overview for UCHL1 antibody (ABIN6938726)

Target: UCHL1 (Ubiquitin Carboxyl-terminal Esterase L1 (Ubiquitin Thiolesterase) (UCHL1))

Reactivity: Human, Rat, Mouse, Cow, Pig, Guinea Pig, Rabbit, Dog, Zebrafish (Danio rerio), Sheep

Host: Mouse

Clonality: Monoclonal

Conjugate: This UCHL1 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: SPM575

Product Details anti-UCHL1 Antibody

Specificity: This MAb reacts with a protein of 20-30 kDa, identified as PGP9.5, also known as ubiquitin carboxyl-terminal hydrolase-1 (UchL1). Initially, PGP9.5 expression in normal tissues was reported in neurons and neuroendocrine cells but later it was found in distal renal tubular epithelium, spermatogonia, Leydig cells, oocytes, melanocytes, prostatic secretory epithelium, ejaculatory duct cells, epididymis, mammary epithelial cells, Merkel cells, and dermal fibroblasts. Furthermore, immunostaining for PGP9.5 has been shown in a wide variety of mesenchymal neoplasms as well. A mutation in PGP9.5 gene is believed to cause a form of Parkinson's disease.

Purification: Purified by Protein A/G

Immunogen: Native UchL1 (PGP9.5) protein from brain

Isotype: IgG2a kappa

Application Details

Application Notes:

Positive Control: Cerebellum.

Known Application: Western Blot (0.5-1 μg/mL), Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Handling

Buffer: 10 mM PBS without BSA and without Azide.

Preservative: Azide free

Storage: 4 °C,-80 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months.

Expiry Date: 24 months

Target Details for UCHL1

Target: UCHL1 (Ubiquitin Carboxyl-terminal Esterase L1 (Ubiquitin Thiolesterase) (UCHL1))

Alternative Name: UCHL1

Molecular Weight: 20-30kDa

Gene ID: 7345

UniProt: P09936

Pathways: Feeding Behaviour