DPP4 antibody

Catalog No. ABIN6939247

This Mouse Monoclonal antibody specifically detects DPP4 in FACS, IHC (fro) and IF. It exhibits reactivity toward Human and Rat.

Quick Overview for DPP4 antibody (ABIN6939247)

Target: DPP4 (Dipeptidyl-Peptidase 4 (DPP4))

Reactivity: Human, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This DPP4 antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (IF)

Clone: 202-36

Product Details anti-DPP4 Antibody

Specificity: Recognizes a glycoprotein of 110 kDa, identified as CD26 (Workshop VI, Code: N-L039). It is an atypical serine protease belonging to the prolyl oligopeptidase family. It is expressed on lymphocyte cells and is upregulated during T-cell activation. CD26 is also expressed on activated B cells and natural killer cells and abundantly on epithelia. CD26 is implicated in a variety of biological functions including T-cell activation, cell adhesion with extracellular matrix such as fibronectin or collagens, and in HIV infection. Cross-linking of CD26 using this antibody dramatically enhances the anti-CD3-induced IL-2 production. In Western blotting, this MAb reacts with only glycosylated CD26, but not with the deglycosylated form. It does not prevent ADA binding to CD26.

No Cross-Reactivity: Pig (Porcine), Sheep (Ovine)

Purification: Purified by Protein A/G

Immunogen: Human T cell clone

Isotype: IgG2b kappa

Application Details

Application Notes:

Positive Control: YT, HEP-G2 cells and lymphocytes. Lymph nodes and tonsils.

Known Application: Flow Cytometry (0.5-1 μg/million cells), Immunofluorescence (0.5-1 μg/mL), Immunohistochemistry (Frozen Only) (0.5-1.0 μg/mL for 30 minutes at RT) Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-80 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Expiry Date: 24 months

Target Details for DPP4

Target: DPP4 (Dipeptidyl-Peptidase 4 (DPP4))

Alternative Name: DPP4

Molecular Weight: 110kDa

Gene ID: 1803

UniProt: P27487

Pathways: Peptide Hormone Metabolism, Regulation of Leukocyte Mediated Immunity