FABP5 antibody
Quick Overview for FABP5 antibody (ABIN6939368)
Target
See all FABP5 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
-
-
Purification
- Purified by Protein A/G
-
Immunogen
- Recombinant human full-length FABP5 protein
-
Isotype
- IgG2a kappa
-
-
-
-
Application Notes
-
Positive Control: MOLT-4 and HEK-293 cell lines. Esophagus, Skin. Keratinocytes, highly expressed in psoriatic skin. Colon.
Known Application: Western Blot (1-2 μg/mL), ,Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT),(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.
-
Restrictions
- For Research Use only
-
-
-
Concentration
- 200 μg/mL
-
Buffer
- 10mM PBS with 0.05% BSA & 0.05% azide.
-
Preservative
- Sodium azide
-
Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Storage
- 4 °C,-80 °C
-
Storage Comment
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
-
Expiry Date
- 24 months
-
-
- FABP5 (Fatty Acid Binding Protein 5 (Psoriasis-Associated) (FABP5))
-
Alternative Name
- FABP5
-
Background
- This gene encodes the fatty acid binding protein found in epidermal cells, and was first identified as being upregulated in psoriasis tissue. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABPs may play roles in fatty acid uptake, transport, and metabolism. Polymorphisms in this gene are associated with type 2 diabetes. The human genome contains many pseudogenes similar to this locus. FABP5 is also associated with poor survival in triple-negative breast cancer. Additionally, FABP5 gene is upregulated in colorectal cancer cells compared to normal colon cells in a manner that correlates with disease stage and that FABP5 significantly promotes colorectal cancer cell growth and metastatic potential.
-
Molecular Weight
- 15.4kDa
-
Gene ID
- 2171
-
UniProt
- Q01469
Target
-