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Recombinant KRT6A antibody

KRT6A Reactivity: Human IHC, StM Host: Mouse Monoclonal rKRT6A-2100 unconjugated Recombinant Antibody
Catalog No. ABIN6939868
  • Target See all KRT6A Antibodies
    KRT6A (Keratin 6A (KRT6A))
    Antibody Type
    Recombinant Antibody
    Reactivity
    • 64
    • 21
    • 11
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 61
    • 15
    • 1
    Mouse
    Clonality
    • 59
    • 18
    Monoclonal
    Conjugate
    • 38
    • 12
    • 9
    • 6
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This KRT6A antibody is un-conjugated
    Application
    • 57
    • 38
    • 25
    • 7
    • 6
    • 6
    • 6
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC), Staining Methods (StM)
    Specificity
    This MAb recognizes a protein of 56 kDa, identified as cytokeratin 6A (KRT6A). In humans, multiple isoforms of Cytokeratin 6 (6A-6F), encoded by several highly homologous genes, have distinct tissue expression patterns. Cytokeratin 6A is the dominant form in epithelial tissue. Cytokeratin 6 and 16 are expressed in keratinocytes, which are undergoing rapid turnover in the suprabasal region (also known as hyper-proliferation-related keratins). Cytokeratin 6 is found in hair follicles, suprabasal cells of a variety of internal stratified epithelia, in epidermis, in both normal and hyper-proliferative situations. Epidermal injury results in activation of keratinocytes, which express KRT6 and KRT16. KRT6 is strongly expressed in about 75 % of head and neck squamous cell carcinomas.
    Purification
    Purified by Protein A/G
    Immunogen
    Recombinant full-length human Cytokeratin 6A (KRT6A) protein
    Clone
    RKRT6A-2100
    Isotype
    IgG1 kappa
    Top Product
    Discover our top product KRT6A Primary Antibody
  • Application Notes

    Positive Control: Tonsil or basal cell carcinoma.

    Known Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

    Restrictions
    For Research Use only
  • Concentration
    200 μg/mL
    Buffer
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-80 °C
    Storage Comment
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    Expiry Date
    24 months
  • Target
    KRT6A (Keratin 6A (KRT6A))
    Alternative Name
    KRT6A (KRT6A Products)
    Synonyms
    CK6A antibody, CK6C antibody, CK6D antibody, K6A antibody, K6C antibody, K6D antibody, KRT6C antibody, KRT6D antibody, 2310016L08Rik antibody, Krt2-6a antibody, Krt2-6c antibody, MK6a antibody, mK6[a] antibody, CK-6A antibody, Krt6a antibody, KRT6A antibody, keratin 6A antibody, similar to keratin complex 2, basic, gene 6a antibody, keratin, type II cytoskeletal 6A antibody, KRT6A antibody, Krt6a antibody, LOC683313 antibody, LOC101112304 antibody
    Molecular Weight
    58kDa
    Gene ID
    3853
    UniProt
    P02538
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