Recombinant RBP4 antibody

Catalog No. ABIN6940485

The Mouse Monoclonal anti-RBP4 antibody has been validated for IHC, StM. It is suitable to detect RBP4 in samples from Human, Mouse, Rat, Rabbit, Monkey, Goat, Chimpanzee.

Quick Overview for Recombinant RBP4 antibody (ABIN6940485)

Target: RBP4 (Retinol Binding Protein 4, Plasma (RBP4))

Antibody Type: Recombinant Antibody

Reactivity: Human, Mouse, Rat, Rabbit, Monkey, Goat, Chimpanzee

Host: Mouse

Clonality: Monoclonal

Conjugate: This RBP4 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Staining Methods (StM)

Clone: RRBP1-872

Product Details anti-RBP4 Antibody

Specificity: This MAb recognizes an epitope within the 74-182 C-terminal sequence (11kD peptide fragment) of human serum Cellular Retinol Binding Protein 1 (CRBP 1), a single-chain glycoprotein belonging to the superfamily of hydrophobic molecule transporter proteins, which is responsible for transport of retinol (vitamin A1) from the liver to peripheral target tissues, like the eye, where it mediates the cellular uptake. CRBP 1 is synthesized by hepatic parenchymal cells where it becomes bound to its ligand retinol and is then released into the circulation, where it binds further to the protein transthyretin, to form a transporting complex, which is big enough not to be lost by filtration through the kidney glomeruli. It is detected in nearly all tissues with higher expression in adult ovary, pancreas, pituitary gland, adrenal gland, and fetal liver.

Purification: Purified by Protein A/G

Immunogen: Recombinant full-length human RBP protein

Isotype: IgG1 kappa

Application Details

Application Notes:

Positive Control: Human Hepatic or Ovarian Carcinoma tissues (IHC).

Known Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-80 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Expiry Date: 24 months

Target Details for RBP4

Target: RBP4 (Retinol Binding Protein 4, Plasma (RBP4))

Alternative Name: RBP

Molecular Weight: 21-25kDa

Gene ID: 5947, 5948, 5950

UniProt: P02753, P09455, P50120

Pathways: Regulatory RNA Pathways, Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis, Production of Molecular Mediator of Immune Response