HPV16 antibody

Catalog No. ABIN6941344

This Mouse Monoclonal antibody specifically detects HPV16 in IHC and IF. It exhibits reactivity toward Human Papillomavirus 16 (HPV-16).

Quick Overview for HPV16 antibody (ABIN6941344)

Target: HPV16 (HPV-16) (Human Papilloma Virus Type 16 (HPV-16))

Reactivity: Human Papillomavirus 16 (HPV-16)

Host: Mouse

Clonality: Monoclonal

Conjugate: This HPV16 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunofluorescence (IF)

Clone: CAMVIR-1

Product Details anti-HPV16 Antibody

Purpose: HPV-16 (Human Papilloma Virus 16) Antibody

Specificity: Reacts with a protein of 57 kDa, identified as the L1 protein of human papilloma virus type 16 (HPV-16). It is the major capsid protein of HPV-16. Infection with specific types of HPV has been associated with an increased risk of developing cervical neoplasia. HPV types 6 and 11 have been associated with relatively benign diseases such as genital warts but types 16 and 18 are strongly associated with cervical, vaginal, and vulvar malignancies. The antibody reacts very strongly with formalin-fixed, paraffin-embedded tissues containing HPV-16 or -33, very weak reactions were occasionally observed with biopsy specimens or smears containing HPV-6 or HPV-11. It cross-reacts with HPV37.

Purification: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Human papilloma virus type 16, major capsid protein L1

Isotype: IgG2a, kappa

Application Details

Application Notes:

Positive Control: HPV-16 infected cells. Cervical tissue.

Known Application: Immunofluorescence (0.5-1 μg/mL), Immunohistochemistry (Formalin-fixed) (0.5-1.0 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Expiry Date: 24 months

Target Details for HPV16

Target: HPV16 (HPV-16) (Human Papilloma Virus Type 16 (HPV-16))

Alternative Name: HPV-16 (Human Papilloma Virus 16)

Target Type: Virus

Background:

HPV-16, HPV-16 capsid, HPV16 L1, HPV16 major capsid protein L1, Human papillomavirus type 16 L1, Human papillomavirus type 16 major capsid protein L1

HPV-16 infected cells. Cervical tissue.

Molecular Weight: 57kDa