Recombinant HPV16 antibody

Catalog No. ABIN6937430

Product Details anti-HPV16 Antibody

Target: HPV16 (HPV-16) (Human Papilloma Virus Type 16 (HPV-16))

Antibody Type: Recombinant Antibody

Reactivity: Virus

Host: Mouse

Clonality: Monoclonal

Conjugate: This HPV16 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Staining Methods (StM)

Specificity: Reacts with a protein of 57 kDa, identified as the L1 protein of human papilloma virus type 16 (HPV-16). It is the major capsid protein of HPV-16. Infection with specific types of HPV has been associated with an increased risk of developing cervical neoplasia. HPV types 6 and 11 have been associated with relatively benign diseases such as genital warts but types 16 and 18 are strongly associated with cervical, vaginal, and vulvar malignancies. The antibody reacts very strongly with formalin-fixed, paraffin-embedded tissues containing HPV-16 or -33, very weak reactions were occasionally observed with biopsy specimens or smears containing HPV-6 or HPV-11. It cross-reacts with HPV37.

Purification: Purified by Protein A/G

Immunogen: Human papilloma virus type 16, major capsid protein L1

Clone: RHPV16L1-1058

Isotype: IgG1 kappa

Application Details

Application Notes:

Positive Control: HPV-16 infected cells. Cervical tissue.

Known Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Handling

Buffer: 10 mM PBS without BSA and without Azide.

Preservative: Azide free

Storage: 4 °C,-80 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months.

Expiry Date: 24 months

Target Details for HPV16

Target: HPV16 (HPV-16) (Human Papilloma Virus Type 16 (HPV-16))

Alternative Name: HPV-16 (Human Papilloma Virus 16) (HPV-16 Products)

Target Type: Virus

Molecular Weight: 57kDa