CD8B antibody

Catalog No. ABIN6941469

Product Details anti-CD8B Antibody

Target: CD8B (CD8b Molecule (CD8B))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This CD8B antibody is un-conjugated

Application: Flow Cytometry (FACS), Functional Studies (Func), Immunofluorescence (IF)

Specificity: This monoclonal antibody reacts with the Mouse CD8 beta molecule. The CD8 beta chain associates with the CD8 alpha chain to form the CD8 alpha/beta heterodimer expressed on the surface of a majority of thymocytes, and on peripheral cytotoxic alpha beta TCR T cells. This monoclonal antibody identifies cytotoxic/suppressor T-cells that interact with MHC class I bearing targets. CD8 is thought to play a role in the process of T-cell mediated killing.

No Cross-Reactivity: Human

Purification: Purified by Protein A/G

Immunogen: Five day mixed leukocyte culture population, C57BL/6 anti-BALB/c

Clone: H35-17-2

Isotype: IgG2b kappa

Application Details

Application Notes:

Positive Control: MPBMC's or Thymus.

Known Application: Functional Studies (Order Antibody without BSA & Azide), Flow Cytometry (0.5-1 μg/million cells in 0.1ml), Immunofluorescence (0.5-1 μg/mL)Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-80 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Expiry Date: 24 months

Target Details for CD8B

Target: CD8B (CD8b Molecule (CD8B))

Alternative Name: Cd8b1 (CD8B Products)

Synonyms: Cd8b antibody, Ly-3 antibody, Ly-C antibody, Lyt-3 antibody, CD8B1 antibody, LEU2 antibody, LY3 antibody, LYT3 antibody, P37 antibody, Cd8b1 antibody, CD8b molecule antibody, CD8 antigen, beta chain 1 antibody, Cd8b antibody, CD8B antibody, Cd8b1 antibody

Molecular Weight: 37kDa

Gene ID: 12526

UniProt: P10300

Pathways: TCR Signaling