Iba1 antibody (C-Term)

Catalog No. ABIN6942056

The Rabbit Monoclonal anti-Iba1 antibody (Clone 9A3) (ABIN6942056) specifically detects Iba1 in WB, IF, IHC (p) and IHC (fro). The antibody is reactive with Mouse samples.

Quick Overview for Iba1 antibody (C-Term) (ABIN6942056)

Target: Iba1 (IBA1) (Ionized Calcium-binding Adapter Molecule 1 (IBA1))

Reactivity: Mouse

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Iba1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: 9A3

Product Details anti-Iba1 Antibody

Binding Specificity: C-Term

Purpose: AIF1 Recombinant Antibody

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: Recombinant protein corresponding to mouse AIF1 aa 100 to the C-terminus

Isotype: IgG

Application Details

Application Notes: WB(1:1000-2000), IHC-P(1:200-1000), IHC-F(1:200-1000), IF(1:200-1000)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for Iba1

Target: Iba1 (IBA1) (Ionized Calcium-binding Adapter Molecule 1 (IBA1))

Alternative Name: AIF1

Background:

Synonyms: Allograft inflammatory factor 1, Ionized calcium-binding adapter molecule 1, AIF-1, AIF1, IBA1.

Background: Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation.

Gene ID: 199

UniProt: P55008

Pathways: Smooth Muscle Cell Migration