AKT2 antibody (AA 21-120) (Cy5.5)

Catalog No. ABIN6942074

This anti-AKT2 antibody is a Rabbit Polyclonal antibody detecting AKT2 in WB, IF (cc) and IF (p). Suitable for Mouse and Rat.

Quick Overview for AKT2 antibody (AA 21-120) (Cy5.5) (ABIN6942074)

Target: AKT2 (V-Akt Murine Thymoma Viral Oncogene Homolog 2 (AKT2))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AKT2 antibody is conjugated to Cy5.5

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-AKT2 Antibody (Cy5.5)

Binding Specificity: AA 21-120

Cross-Reactivity: Mouse, Rat

Predicted Reactivity: Cow,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human AKT2

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for AKT2

Target: AKT2 (V-Akt Murine Thymoma Viral Oncogene Homolog 2 (AKT2))

Alternative Name: AKT2

Background:

Synonyms: C AKT, MGC9965, Oncogene AKT1, PKB, PRKBA, Protein Kinase B Alpha, RAC, RAC PK Alpha, RAC Serine/Threonine Protein Kinase, vAKT Murine Thymoma Viral Oncogene Homolog 1, AKT2_HUMAN, HIHGHH, AKT 2, AKT-2, Akt2, PKB beta, PKB-beta, PKBB, PKBBETA, PRKBB, Protein kinase Akt 2, Protein kinase Akt-2, Protein kinase B beta, RAC BETA, RAC beta serine threonine protein kinase, RAC PK beta, Rac protein kinase beta, Rac protein kinase beta, RAC-BETA, RAC-beta serine/threonine-protein kinase, RAC-PK-beta, V AKT Murine Thymoma Viral Oncogene Homolog 2.

Background: This gene is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains. The gene was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. The encoded protein is a general protein kinase capable of phophorylating several known proteins. [provided by RefSeq, Jul 2008].

Gene ID: 208

UniProt: P31751

Pathways: PI3K-Akt Signaling, RTK Signaling, AMPK Signaling, TLR Signaling, Cellular Glucan Metabolic Process, Regulation of Carbohydrate Metabolic Process, Hepatitis C, VEGF Signaling