Calnexin antibody

Catalog No. ABIN6942330

This Rabbit Monoclonal antibody specifically detects Calnexin in WB, IHC, FACS, IHC (p) and IF (cc). It exhibits reactivity toward Human and Rat.

Quick Overview for Calnexin antibody (ABIN6942330)

Target: Calnexin (CANX)

Reactivity: Human, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Calnexin antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Clone: 24G6

Product Details anti-Calnexin Antibody

Cross-Reactivity: Human, Rat

Purification: Purified by Protein A.

Immunogen: C terminus human Calnexin

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
FCM 1:20-100
IHC-P 1:200-400
IF(ICC) 1:50-200
IHC()

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for Calnexin

Target: Calnexin (CANX)

Alternative Name: Calnexin

Background:

Synonyms: Calnexin, IP90, Major histocompatibility complex class I antigen-binding protein p88, p90, CANX

Background: Calcium-binding protein that interacts with newly synthesized glycoproteins in the endoplasmic reticulum. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins. Associated with partial T-cell antigen receptor complexes that escape the ER of immature thymocytes, it may function as a signaling complex regulating thymocyte maturation. Additionally it may play a role in receptor-mediated endocytosis at the synapse.

Gene ID: 821

UniProt: P27824

Pathways: MAPK Signaling, Thyroid Hormone Synthesis