CD4 antibody (AA 31-130) (Biotin)

Catalog No. ABIN6942436

The Rabbit Polyclonal anti-CD4 antibody has been validated for WB, IHC (fro) and IHC (p). It is suitable to detect CD4 in samples from Mouse.

Quick Overview for CD4 antibody (AA 31-130) (Biotin) (ABIN6942436)

Target: CD4

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD4 antibody is conjugated to Biotin

Application: Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-CD4 Antibody (Biotin)

Binding Specificity: AA 31-130

Cross-Reactivity: Mouse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from mouse CD4

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for CD4

Target: CD4

Alternative Name: CD4

Background:

Synonyms: CD4 (L3T4), CD4 antigen (p55), CD4 Antigen , CD4 Molecule, CD4 Receptor, CD4+ Lymphocyte deficiency, included, CD4mut, L3T4, Leu3, Ly-4, Lymphocyte antigen CD4, MGC165891, p55, T Cell Antigen T4 , T cell antigen T4/LEU3, T cell differentiation antigen L3T4, T cell OKT4 deficiency, included, T cell surface antigen T4/Leu 3 , T cell surface antigen T4/Leu3, T Cell Surface Glycoprotein CD4, W3/25, W3/25 antigen, T-cell surface glycoprotein CD4 isoform 1 precursor, CD4_MOUSE.

Background: This gene encodes a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigenes and is also a receptor for the human immunodeficiency virus. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, and granulocytes. It is also expressed in specific regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene. [provided by RefSeq, Aug 2010].

Gene ID: 12504

UniProt: P06332

Pathways: TCR Signaling, Maintenance of Protein Location, CXCR4-mediated Signaling Events