Recombinant Desmoglein 1 antibody (C-Term)

Catalog No. ABIN6943132

The Rabbit Monoclonal anti-Desmoglein 1 antibody is suitable to detect Desmoglein 1 in samples from Human. It has been validated for WB, IF, IHC (p) and IHC (fro).

Quick Overview for Recombinant Desmoglein 1 antibody (C-Term) (ABIN6943132)

Target: Desmoglein 1 (DSG1)

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Desmoglein 1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-Desmoglein 1 Antibody

Binding Specificity: C-Term

Purpose: Desmoglein 1 Recombinant Antibody

Predicted Reactivity: Human,Mouse,Rat

Purification: Purified by Protein A.

Immunogen: Recombinant protein within human DSG1 aa 900 to the C-terminus

Isotype: IgG

Application Details

Application Notes: WB(1:500-2000), IHC-P(1:100-500), IHC-F(1:100-500), IF(1:100-500)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: 0.01M TBS ( pH 7.4), 1 % BSA, 0.02 % Proclin 300, and 50 % Glycerol

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 12 months

Target Details for Desmoglein 1

Target: Desmoglein 1 (DSG1)

Alternative Name: DSG1

Background:

Synonyms: Desmoglein-1, Cadherin family member 4, Desmosomal glycoprotein 1, Pemphigus foliaceus antigen, DG1, DGI, DSG1, CDHF4

Background: Desmogleins (dsgs) are type I membrane proteins that are important for cell adhesion and are expressed in great abundance at the desmosomes, which are adhesive cell junctions. DSG1 is a component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.

Gene ID: 1828

UniProt: Q02413

Pathways: Cell-Cell Junction Organization