Recombinant S1PR1 antibody (AA 303-382)

Catalog No. ABIN6943205

The Rabbit Monoclonal anti-S1PR1 antibody (ABIN6943205) specifically detects S1PR1 in WB. The antibody is reactive with Human samples.

Quick Overview for Recombinant S1PR1 antibody (AA 303-382) (ABIN6943205)

Target: S1PR1 (Sphingosine-1-Phosphate Receptor 1 (S1PR1))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This S1PR1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-S1PR1 Antibody

Binding Specificity: AA 303-382

Purpose: EDG1 Recombinant Antibody

Cross-Reactivity: Human

Purification: Purified by Protein A.

Immunogen: Human EDG1 aa 303-382

Isotype: IgG

Application Details

Application Notes: WB(1:500-2000)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: 0.01M TBS ( pH 7.4), 1 % BSA, 0.02 % Proclin 300, and 50 % Glycerol

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for S1PR1

Target: S1PR1 (Sphingosine-1-Phosphate Receptor 1 (S1PR1))

Alternative Name: EDG1

Background:

Synonyms: Sphingosine 1-phosphate receptor 1, Endothelial differentiation G-protein coupled receptor 1, Sphingosine 1-phosphate receptor Edg-1, S1P receptor 1, S1P1, S1P receptor Edg-1, S1PR1

Background: This gene encodes a protein that may regulate endothelial cell differentiation, lipid metabolism, and hormone-induced cardiomyocyte hypertrophy. The encoded protein has also been found to act as a transcriptional coactivator by interconnecting the general transcription factor TATA element-binding protein (TBP) and gene-specific activators. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]

Gene ID: 1901

UniProt: P21453

Pathways: Signaling Events mediated by VEGFR1 and VEGFR2