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Frataxin antibody

FXN Reactivity: Human WB Host: Rabbit Monoclonal 2G1 unconjugated
Catalog No. ABIN6943478
  • Target See all Frataxin (FXN) Antibodies
    Frataxin (FXN)
    Reactivity
    • 63
    • 22
    • 13
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 57
    • 13
    Rabbit
    Clonality
    • 60
    • 10
    Monoclonal
    Conjugate
    • 39
    • 6
    • 6
    • 5
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Frataxin antibody is un-conjugated
    Application
    • 53
    • 39
    • 21
    • 10
    • 6
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Cross-Reactivity
    Human
    Purification
    Purified by Protein A.
    Immunogen
    Full length recombinant human Frataxin protein
    Clone
    2G1
    Isotype
    IgG
    Top Product
    Discover our top product FXN Primary Antibody
  • Application Notes
    WB 1:300-5000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C for 12 months.
    Expiry Date
    12 months
  • Target
    Frataxin (FXN)
    Alternative Name
    FRATAXIN (FXN Products)
    Synonyms
    zgc:158218 antibody, LOC100284365 antibody, BcDNA:AT09528 antibody, CG8971 antibody, DFH antibody, Dfh antibody, Dmel\\CG8971 antibody, X25 antibody, dfh antibody, CyaY antibody, FA antibody, FARR antibody, FRDA antibody, RGD1565754 antibody, Frda antibody, frataxin antibody, fxn antibody, LOC100284365 antibody, TVAG_182150 antibody, fh antibody, FTX1 antibody, FXN antibody, Fxn antibody
    Background

    Synonyms: Frataxin, mitochondrial, FXN, Friedreich ataxia protein, FRDA, X25

    Background: Promotes the biosynthesis of heme and assembly and repair of iron-sulfur clusters by delivering Fe2+ to proteins involved in these pathways. May play a role in the protection against iron-catalyzed oxidative stress through its ability to catalyze the oxidation of Fe2+ to Fe3+, the oligomeric form but not the monomeric form has in vitro ferroxidase activity. May be able to store large amounts of iron in the form of a ferrihydrite mineral by oligomerization, however, the physiological relevance is unsure as reports are conflicting and the function has only been shown using heterologous overexpression systems. Modulates the RNA-binding activity of ACO1.

    Gene ID
    2395
    UniProt
    Q16595
    Pathways
    Transition Metal Ion Homeostasis, Regulation of Cell Size
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