Recombinant ITGA2 antibody (AA 1-100)

Catalog No. ABIN6943808

The Rabbit Monoclonal anti-ITGA2 antibody (ABIN6943808) specifically detects ITGA2 in WB, IF, ICC, IHC (p) and IHC (fro). The antibody is reactive with Human samples.

Quick Overview for Recombinant ITGA2 antibody (AA 1-100) (ABIN6943808)

Target: ITGA2 (Integrin alpha 2 (ITGA2))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This ITGA2 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-ITGA2 Antibody

Binding Specificity: AA 1-100

Purpose: Integrin alpha 2 Recombinant Antibody

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: Recombinant protein within Human Integrin alpha 2 aa 1-100

Isotype: IgG

Application Details

Application Notes: WB(1:300-5000), IHC-P(1:20-100), IHC-F(1:100-500), IF(), ICC/IF(1:50-100)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.01M TBS ( pH 7.4), 1 % BSA, 0.02 % Proclin 300, and 50 % Glycerol

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for ITGA2

Target: ITGA2 (Integrin alpha 2 (ITGA2))

Alternative Name: Integrin alpha 2

Background:

Synonyms: Integrin alpha-2, CD49 antigen-like family member B, Collagen receptor, Platelet membrane glycoprotein Ia, VLA-2 subunit alpha, CD_antigen: CD49b, GPIa, ITGA2

Background: Integrin alpha-2/beta-1 is a receptor for laminin, collagen, collagen C-propeptides, fibronectin and E-cadherin. It recognizes the proline-hydroxylated sequence G-F-P-G-E-R in collagen. It is responsible for adhesion of platelets and other cells to collagens, modulation of collagen and collagenase gene expression, force generation and organization of newly synthesized extracellular matrix.

Gene ID: 3673

UniProt: P17301

Pathways: CXCR4-mediated Signaling Events, Smooth Muscle Cell Migration, Integrin Complex