Ki-67 antibody

Catalog No. ABIN6943883

The Rabbit Monoclonal anti-Ki-67 antibody (Clone 6G6) (ABIN6943883) specifically detects Ki-67 in IHC, WB and FACS. The antibody is reactive with Human and Mouse samples.

Quick Overview for Ki-67 antibody (ABIN6943883)

Target: Ki-67 (MKI67) (Antigen Identified By Monoclonal Antibody Ki-67 (MKI67))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Ki-67 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Western Blotting (WB), Flow Cytometry (FACS)

Clone: 6G6

Product Details anti-Ki-67 Antibody

Purification: Purified by Protein A.

Immunogen: Recombinant protein

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
FCM 1:20-100
IHC()

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C

Expiry Date: 12 months

Target Details for Ki-67

Target: Ki-67 (MKI67) (Antigen Identified By Monoclonal Antibody Ki-67 (MKI67))

Alternative Name: Ki67

Background:

Proliferation Marker Ki67 antigen is the prototypic cell cycle related nuclear protein, expressed by proliferating cells in all phases of the active cell cycle (G1, S, G2 and M phase). It is absent in resting (G0) cells. Ki67 are useful in establishing the cell growing fraction in neoplasms (immunohistochemically quantified by determining the number of Ki67 positive cells among the total number of resting cells = Ki67 index). In neoplastic tissues the prognostic value is comparable to the tritiated thymidine labelling index. The correlation between low Ki67 index and histologically low grade tumours is strong. Ki67 is routinely used as a neuronal marker of cell cycling and proliferation.

Synonyms: Antigen KI-67, MKI67, Antigen identified by monoclonal antibody Ki-67, Proliferation marker protein Ki-67

Gene ID: 4288

UniProt: P46013

Pathways: Glycosaminoglycan Metabolic Process