MCCC2 antibody (AA 351-450) (HRP)

Catalog No. ABIN6944040

This Rabbit Polyclonal antibody specifically detects MCCC2 in WB. It exhibits reactivity toward Human, Mouse and Xenopus tropicalis.

Quick Overview for MCCC2 antibody (AA 351-450) (HRP) (ABIN6944040)

Target: MCCC2 (Methylcrotonoyl-CoA Carboxylase 2 (Beta) (MCCC2))

Reactivity: Human, Mouse, Xenopus tropicalis

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MCCC2 antibody is conjugated to HRP

Application: Western Blotting (WB)

Product Details anti-MCCC2 Antibody (HRP)

Binding Specificity: AA 351-450

Cross-Reactivity: Human, Mouse, Xenopus tropicalis

Predicted Reactivity: Rat,Dog,Cow,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human MCCC2

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for MCCC2

Target: MCCC2 (Methylcrotonoyl-CoA Carboxylase 2 (Beta) (MCCC2))

Alternative Name: MCCC2

Background:

Synonyms: 3 methylcrotonyl CoA carboxylase 2, 3 methylcrotonyl CoA carboxylase non biotin containing subunit, 3 methylcrotonyl CoA:carbon dioxide ligase subunit beta, 3-methylcrotonyl-CoA carboxylase 2, 3-methylcrotonyl-CoA carboxylase non-biotin-containing subunit, 3-methylcrotonyl-CoA:carbon dioxide ligase subunit beta, Biotin carboxylase, MCCase subunit beta, MCCB, MCCB_HUMAN, MCCC 2, Mccc2, Methylcrotonoyl CoA carboxylase 2 (beta), Methylcrotonoyl CoA carboxylase beta chain mitochondrial, Methylcrotonoyl Coenzyme A carboxylase 2 (beta), Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial, Non biotin containing subunit of 3 methylcrotonyl CoA carboxylase.

Background: This gene encodes the small subunit of 3-methylcrotonyl-CoA carboxylase. This enzyme functions as a heterodimer and catalyzes the carboxylation of 3-methylcrotonyl-CoA to form 3-methylglutaconyl-CoA. Mutations in this gene are associated with 3-Methylcrotonylglycinuria, an autosomal recessive disorder of leucine catabolism.

Gene ID: 64087

UniProt: Q9HCC0