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PICK1 antibody

PICK1 Reactivity: Human, Mouse, Rat WB, IP, FACS Host: Rabbit Monoclonal 4G1 unconjugated
Catalog No. ABIN6944547
  • Target See all PICK1 Antibodies
    PICK1 (Protein Interacting With Protein Kinase C, alpha 1 (PICK1))
    Reactivity
    • 43
    • 31
    • 13
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 40
    • 5
    • 1
    Rabbit
    Clonality
    • 36
    • 10
    Monoclonal
    Conjugate
    • 25
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PICK1 antibody is un-conjugated
    Application
    • 33
    • 23
    • 11
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP), Flow Cytometry (FACS)
    Cross-Reactivity
    Human, Mouse, Rat
    Purification
    Purified by Protein A.
    Immunogen
    Recombinant protein within N-terminal human PICK1.
    Clone
    4G1
    Isotype
    IgG
    Top Product
    Discover our top product PICK1 Primary Antibody
  • Application Notes
    WB 1:300-5000
    FCM 1:20-100
    IP(1-2 μg)
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Expiry Date
    12 months
  • Target
    PICK1 (Protein Interacting With Protein Kinase C, alpha 1 (PICK1))
    Alternative Name
    PICK1 (PICK1 Products)
    Synonyms
    PICK antibody, PRKCABP antibody, Prkcabp antibody, prkcabp antibody, MGC131295 antibody, PICK1 antibody, DKFZp470L2127 antibody, protein interacting with PRKCA 1 antibody, protein interacting with C kinase 1 antibody, protein interacting with PRKCA 1 L homeolog antibody, PICK1 antibody, Pick1 antibody, pick1 antibody, pick1.L antibody
    Background

    Synonyms: PRKCA-binding protein, Protein interacting with C kinase 1, protein interacting with PRKCA 1, Protein kinase C-alpha-binding protein, PICK1, PRKCABP

    Background: Probable adapter protein that bind to and organize the subcellular localization of a variety of membrane proteins containing some PDZ recognition sequence. Involved in the clustering of various receptors, possibly by acting at the receptor internalization level. Plays a role in synaptic plasticity by regulating the trafficking and internalization of AMPA receptors. May be regulated upon PRKCA activation. May regulate ASIC1/ASIC3 channel. Regulates actin polymerization by inhibiting the actin-nucleating activity of the Arp2/3 complex, the function is competetive with nucleation promoting factors and is linked to neuronal morphology regulation and AMPA receptor (AMPAR) endocytosis. Via interaction with the Arp2/3 complex involved in regulation of synaptic plasicity of excitatory synapses and required for spine shrinkage during long-term depression (LTD). Involved in regulation of astrocyte morphology, antagonistic to Arp2/3 complex activator WASL/N-WASP function.

    Gene ID
    9463
    UniProt
    Q9NRD5
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