PNMA3 antibody (AA 351-450) (Biotin)

Catalog No. ABIN6944624

This anti-PNMA3 antibody is a Rabbit Polyclonal antibody detecting PNMA3 in WB, ELISA, IHC (p) and IHC (fro). Suitable for Mouse.

Quick Overview for PNMA3 antibody (AA 351-450) (Biotin) (ABIN6944624)

Target: PNMA3 (Paraneoplastic Antigen MA3 (PNMA3))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PNMA3 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-PNMA3 Antibody (Biotin)

Binding Specificity: AA 351-450

Cross-Reactivity: Mouse

Predicted Reactivity: Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from mouse PNMA3

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for PNMA3

Target: PNMA3 (Paraneoplastic Antigen MA3 (PNMA3))

Alternative Name: PNMA3

Background:

Synonyms: MA3, MA5, MGC132756, MGC132758, Paraneoplastic antigen Ma3, Paraneoplastic cancer testis brain antigen, Paraneoplastic Ma antigen 3, PNMA 3, PNMA3, PNMA3_MOUSE.

Background: The protein encoded by this gene belongs to the paraneoplastic antigen MA (PNMA) family, which shares homology with retroviral Gag proteins. The PNMA antigens are highly expressed in the brain and also in a range of tumors associated with serious neurological phenotypes. PMID:16407312 reports the presence of a functional -1 ribosomal frameshift signal (consisting of a heptanucleotide shift motif followed 3' by a pseudoknot structure) in this gene, however, the frame-shifted product has not been characterized. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2013]

Gene ID: 245468

UniProt: Q8JZW8