T-Box 19 antibody (AA 200-400)

Catalog No. ABIN6945138

This Rabbit Monoclonal antibody specifically detects T-Box 19 in WB, IHC (p), IP, FACS and IF (cc). It exhibits reactivity toward Human.

Quick Overview for T-Box 19 antibody (AA 200-400) (ABIN6945138)

Target: T-Box 19 (TBX19)

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This T-Box 19 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc))

Clone: 1F11

Product Details anti-T-Box 19 Antibody

Binding Specificity: AA 200-400

Purpose: TBXT Recombinant Antibody

Cross-Reactivity: Human, Mouse

Purification: Purified by Protein A.

Immunogen: Recombinant protein within human TBXT aa 200-400.

Isotype: IgG

Application Details

Application Notes: WB(1:300-5000), FCM(1:20-100), IHC-P(1:200-400), IF(ICC)(1:50-200), IP(1-2 μg)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for T-Box 19

Target: T-Box 19 (TBX19)

Alternative Name: TBXT

Background:

Synonyms: T-box transcription factor T, TBXT, Brachyury protein

Background: TBXTis an embryonic nuclear transcription factor that binds to a specific DNA element, the palindromic T-site. It binds through a region in its N-terminus, called the T-box, and effects transcription of genes required for mesoderm formation and differentiation. The protein is localized to notochord-derived cells. Variation in this gene was associated with susceptibility to neural tube defects and chordoma. A mutation in this gene was found in a family with sacral agenesis with vertebral anomalies. Involved in the transcriptional regulation of genes required for mesoderm formation and differentiation.

Gene ID: 6862

UniProt: O15178