Growth Hormone 1 antibody

Catalog No. ABIN6950857

The Mouse Monoclonal anti-Growth Hormone 1 antibody is suitable to detect Growth Hormone 1 in samples from Human. It has been validated for IHC.

Quick Overview for Growth Hormone 1 antibody (ABIN6950857)

Target: Growth Hormone 1 (GH1)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Growth Hormone 1 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Product Details anti-Growth Hormone 1 Antibody

Purpose: GH/ hPL mouse mAb

Specificity: The antibody can recognize human Placental lactogen, and has cross-reactiin with GH protein.

Purification: The antibody was purified by affinity chromatography using a specific immunogen.

Immunogen: A synthetic peptide corresponding to the amino acid region 150 - 217 of the human GH/ hPL protein.

Isotype: IgG

Application Details

Application Notes: IHC, 1:200-1:400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze / thaw cycles

Storage: -20 °C

Storage Comment: Store at-20°C. Avoid freeze / thaw cycles.

Target Details for Growth Hormone 1

Target: Growth Hormone 1 (GH1)

Alternative Name: Growth Hormone (GH)

Background:

Synonyms: Lactogen, Placental lactogen, PL, hPL, gH, GH-N, GH1, GHB5, GHN, Growth hormone 1, Growth hormone, Growth hormone B5, Growth hormone, normal, Growth hormone, pituitary, HG1, hGH-N, IGHD1B, Pituitary growth hormone, RNGHGP, SOMA_HUMAN, Somatotropin

Background: Human placental prolactin (HPL) is a 22 kD polypeptide hormone synthesized and secreted by placental syncytiotrophoblast cells, has partial homology with growth hormone. It is expressed in normal placenta, choriocarcinoma, testicular cancer. Anti-HPL antibody is commonly used in the study of trophoblastic tumors. Growth hormone (GH) is a hormone synthesized and secreted by growth hormone cells in the anterior pituitary, which can promote protein synthesis and bone development. The mechanism of stimulating body growth is to stimulate the secretion of IGF-1 by liver and other tissues. It is mainly used for the functional classification of pituitary tumor and the differentiation of primary pituitary tumor and metastatic cancer.

Gene Name: CSH1 CSH2 GH1

Protein Name: GH/ hPL

UniProt: P01241

Pathways: NF-kappaB Signaling, JAK-STAT Signaling, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Hormone Metabolic Process, Response to Growth Hormone Stimulus, Regulation of Hormone Biosynthetic Process