IL-6 antibody (Biotin)

Catalog No. ABIN6963818

This Rat Monoclonal antibody specifically detects IL-6 in ELISA and ELISpot. It exhibits reactivity toward Mouse and has been mentioned in 3+ publications.

Quick Overview for IL-6 antibody (Biotin) (ABIN6963818)

Target: IL-6 (IL6) (Interleukin 6 (IL6))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This IL-6 antibody is conjugated to Biotin

Application: ELISA, ELISpot

Clone: 32C11

Product Details anti-IL-6 Antibody (Biotin)

Specificity: Native and recombinant IL-6

Purification: Biotinylated through reaction with a N-hydroxysuccinimide ester of biotin.,Purified from in vitro cultures by protein G affinity chromatography.

Sterility: 0.2 μm filtered

Immunogen: Recombinant mouse IL-6

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: supplied at 0.5 mg/mL in PBS with 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store product at 4-8°C or frozen at -20°C or below. Avoid repeated freezing/ thawing.

Expiry Date: 18 months

References for anti-IL-6 antibody (Biotin) (ABIN6963818)

Wang, Smith, Cao, Chen, Acosta, Chichester, Yusibov, Streatfield, Fattom, Baker: "Recombinant H5 hemagglutinin adjuvanted with nanoemulsion protects ferrets against pathogenic avian influenza virus challenge." in: Vaccine, Vol. 37, Issue 12, pp. 1591-1600, (2020) (PubMed).

Li, Chi, Huang, Yan, Zhang, Liu, Wang, Li, Zhang, Mo, Jin, Wang, Feng, Wang, Bi, Wang, Sun, Gao, Zhao, Yang, Xia: "A Novel Bacterium-Like Particle Vaccine Displaying the MERS-CoV Receptor-Binding Domain Induces Specific Mucosal and Systemic Immune Responses in Mice." in: Viruses, Vol. 11, Issue 9, (2020) (PubMed).

Breyner, Michon, de Sousa, Vilas Boas, Chain, Azevedo, Langella, Chatel: "Microbial Anti-Inflammatory Molecule (MAM) from Faecalibacterium prausnitzii Shows a Protective Effect on DNBS and DSS-Induced Colitis Model in Mice through Inhibition of NF-κB Pathway." in: Frontiers in microbiology, Vol. 8, pp. 114, (2017) (PubMed).

Target Details for IL-6

Target: IL-6 (IL6) (Interleukin 6 (IL6))

Alternative Name: IL6

Gene ID: 16193

Pathways: TLR Signaling, Hormone Transport, Negative Regulation of Hormone Secretion, Myometrial Relaxation and Contraction, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Regulation of Carbohydrate Metabolic Process, Autophagy, Cell RedoxHomeostasis, Cancer Immune Checkpoints, Inflammasome