IL-13 antibody (Biotin)

Catalog No. ABIN6963883

Cited in 4+ publications. The Biotin-conjugated Rat Monoclonal anti-IL-13 antibody (Clone 25K2) (ABIN6963883) specifically detects IL-13 in ELISpot. The antibody is reactive with Human samples.

Quick Overview for IL-13 antibody (Biotin) (ABIN6963883)

Target: IL-13 (IL13) (Interleukin 13 (IL13))

Reactivity: Human

Host: Rat

Clonality: Monoclonal

Conjugate: This IL-13 antibody is conjugated to Biotin

Application: ELISpot

Clone: 25K2

Product Details anti-IL-13 Antibody (Biotin)

Specificity: Native and recombinant IL-13

Purification: Biotinylated through reaction with a N-hydroxysuccinimide ester of biotin.,Purified from in vitro cultures by protein G affinity chromatography.

Sterility: 0.2 μm filtered

Immunogen: Recombinant human IL-13

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: supplied at 0.5 mg/mL in PBS with 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store product at 4-8°C or frozen at -20°C or below. Avoid repeated freezing/ thawing.

Expiry Date: 18 months

References for anti-IL-13 antibody (Biotin) (ABIN6963883)

Jarrett, Salio, Lloyd-Lavery, Subramaniam, Bourgeois, Archer, Cheung, Hardman, Chandler, Salimi, Gutowska-Owsiak, de la Serna, Fallon, Jolin, Mckenzie, Dziembowski, Podobas, Bal, Johnson, Moody et al.: "Filaggrin inhibits generation of CD1a neolipid antigens by house dust mite-derived phospholipase. ..." in: Science translational medicine, Vol. 8, Issue 325, pp. 325ra18, (2016) (PubMed).

Subramaniam, Aslam, Misbah, Salio, Cerundolo, Moody, Ogg: "Elevated and cross-responsive CD1a-reactive T cells in bee and wasp venom allergic individuals." in: European journal of immunology, Vol. 46, Issue 1, pp. 242-52, (2016) (PubMed).

Persson, Ekerfelt, Jablonowska, Jonsson, Ernerudh, Jenmalm, Berg: "Immunological status in patients undergoing in vitro fertilisation: responses to hormone treatment and relationship to outcome." in: Journal of reproductive immunology, Vol. 96, Issue 1-2, pp. 58-67, (2013) (PubMed).

Xue, Barrow, Fleming, Hunter, Ogg, Klenerman, Pettipher: "Leukotriene E4 activates human Th2 cells for exaggerated proinflammatory cytokine production in response to prostaglandin D2." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 188, Issue 2, pp. 694-702, (2012) (PubMed).

Target Details for IL-13

Target: IL-13 (IL13) (Interleukin 13 (IL13))

Alternative Name: IL13

Gene ID: 3596

Pathways: JAK-STAT Signaling, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Proton Transport