IL-13 antibody

Catalog No. ABIN6964025

This Rat Monoclonal antibody specifically detects IL-13 in Neut. It exhibits reactivity toward Human and Non-Human Primate and has been mentioned in 2+ publications.

Quick Overview for IL-13 antibody (ABIN6964025)

Target: IL-13 (IL13) (Interleukin 13 (IL13))

Reactivity: Human, Non-Human Primate

Host: Rat

Clonality: Monoclonal

Conjugate: This IL-13 antibody is un-conjugated

Application: Neutralization (Neut)

Clone: 5A2

Product Details anti-IL-13 Antibody

Specificity: Native and recombinant IL-13

Cross-Reactivity (Details): The antibody cross-reacts with IL-13 from non-human primates. Cross-reactivity has been tested in ELISA and/or ELISpot.

Purification: Purified from in vitro cultures by protein G affinity chromatography.

Immunogen: Recombinant human IL-13

Isotype: IgG1

Application Details

Application Notes: Neutralization of human IL-13 bioactivity. It is recommended to establish the optimal antibody concentration for the assay system used.

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: supplied at 1 mg/mL in PBS free of preservatives

Preservative: Without preservative

Storage: 4 °C,-20 °C

Storage Comment: Store product at 4-8°C or frozen at -20°C or below. Avoid repeated freezing/ thawing.

Expiry Date: 18 months

References for anti-IL-13 antibody (ABIN6964025)

Akdis, Simon, Weigl, Kreyden, Blaser, Akdis: "Skin homing (cutaneous lymphocyte-associated antigen-positive) CD8+ T cells respond to superantigen and contribute to eosinophilia and IgE production in atopic dermatitis." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 163, Issue 1, pp. 466-75, (1999) (PubMed).

Punnonen, Yssel, de Vries: "The relative contribution of IL-4 and IL-13 to human IgE synthesis induced by activated CD4+ or CD8+ T cells." in: The Journal of allergy and clinical immunology, Vol. 100, Issue 6 Pt 1, pp. 792-801, (1998) (PubMed).

Target Details for IL-13

Target: IL-13 (IL13) (Interleukin 13 (IL13))

Alternative Name: IL13

Gene ID: 3596

Pathways: JAK-STAT Signaling, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Proton Transport