MAZ antibody

Catalog No. ABIN6972313

The Mouse Monoclonal anti-MAZ antibody (Clone 133) (ABIN6972313) specifically detects MAZ in WB, ChIP and SSA. The antibody is reactive with Human samples.

Quick Overview for MAZ antibody (ABIN6972313)

Target: MAZ (MYC-Associated Zinc Finger Protein (Purine-Binding Transcription Factor) (MAZ))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This MAZ antibody is un-conjugated

Application: Western Blotting (WB), Chromatin Immunoprecipitation (ChIP), Supershift Assay (SSA)

Clone: 133

Product Details anti-MAZ Antibody

Characteristics: MAZ (Myc-associated zinc finger protein) functions as a transcription factor roles in both transcription initiation and termination. MAZ binds to two sites within the c-Myc promoter, ME1a1 and ME1a2. It also binds to multiple G/C-rich sites within the promoter of the Sp1 family of transcription factors. MAZ also participates in skeletal muscle development through the activation of several skeletal muscle-specific genes. MAZ has also been reported to drive tumor-specific expression of PPAR-gamma in breast cancer cells. MAZ antibody (mAb) (Clone 133) was raised in a Mouse host. It has been validated for use in Chromatin Immunoprecipitation, Supershift and Western blot, it has been shown to react with Human samples.

Purification: Protein G Chromatography

Immunogen: This MAZ antibody was raised against recombinant human MAZ protein.

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: Purified IgG in 70 mM Tris ( pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30 % glycerol and 0.035 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Target Details for MAZ

Target: MAZ (MYC-Associated Zinc Finger Protein (Purine-Binding Transcription Factor) (MAZ))

Alternative Name: MAZ

Molecular Weight: 55 kDa

NCBI Accession: NP_002374

Pathways: Chromatin Binding