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MYCN antibody (C-Term)

MYCN Reactivity: Human WB, ChIP-seq Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6972393
  • Target See all MYCN Antibodies
    MYCN (N-Myc Proto-Oncogene Protein (MYCN))
    Binding Specificity
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 30
    • 17
    • 14
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 28
    • 7
    Rabbit
    Clonality
    • 30
    • 5
    Polyclonal
    Conjugate
    • 25
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MYCN antibody is un-conjugated
    Application
    • 23
    • 14
    • 6
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ChIP DNA-Sequencing (ChIP-seq)
    Characteristics
    N-Myc (MYCN) is a member of the Myc family of proto-oncogenes. Myc family members play crucial roles in regulating cell proliferation, size and differentiation. N-Myc is required for proper development of the nervous system. Myc family proteins can induce malignant transformation inappropriately modulating gene transcription, leading to unchecked cell proliferation. Misexpression of N-Myc is often associated with pediatric neural cancers such as neuroblastoma, medulloblastoma and retinoblastoma. N-Myc antibody (pAb) was raised in a Rabbit host. It has been validated for use in ChIP-Seq and Western blot, it has been shown to react with Human samples.
    Purification
    Affinity Purified
    Immunogen
    This N-Myc antibody was raised against a peptide derived from the C-terminal region of human N-Myc.
    Isotype
    IgG
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  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Buffer
    Purified IgG in 70 mM Tris ( pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30 % glycerol and 0.035 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
  • Target
    MYCN (N-Myc Proto-Oncogene Protein (MYCN))
    Alternative Name
    N-Myc (MYCN Products)
    Synonyms
    MODED antibody, MYCNOT antibody, N-myc antibody, NMYC antibody, ODED antibody, bHLHe37 antibody, Nmyc antibody, Nmyc-1 antibody, Nmyc1 antibody, c-nmyc antibody, Nmuc1 antibody, fb57a02 antibody, nmyc1 antibody, wu:fb57a02 antibody, zgc:85706 antibody, XN-myc antibody, XNmyc antibody, mycn antibody, mycn-a antibody, mycn-b antibody, mycna antibody, xN-myc1 antibody, MYCN proto-oncogene, bHLH transcription factor antibody, v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog antibody, v-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived antibody, olfactory receptor 8S1 antibody, MYCN proto-oncogene, bHLH transcription factor S homeolog antibody, MYCN antibody, Mycn antibody, LOC515887 antibody, mycn antibody, mycn.S antibody
    Molecular Weight
    60 kDa
    NCBI Accession
    NP_005369
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