RAR-alpha (AA 413-448) antibody

Catalog No. ABIN6972583

The Mouse Monoclonal anti-RAR-alpha antibody (Clone 8B-10B2) (ABIN6972583) specifically detects RAR-alpha in IHC, SSA and WB. The antibody is reactive with Human samples.

Quick Overview for RAR-alpha (AA 413-448) antibody (ABIN6972583)

Target: RAR-alpha

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: Un-conjugated

Application: Immunohistochemistry (IHC), Supershift Assay (SSA), Western Blotting (WB)

Clone: 8B-10B2

Product Details

Binding Specificity: AA 413-448

Characteristics: RAR-b (HAP, NR1B2) is a member of the thyroid-steroid hormone receptor superfamily of nuclear transcriptional regulators. RAR-b localizes to the cytoplasm and to subnuclear compartments. RAR-b binds retinoic acid, the biologically active form of vitamin A which mediates cellular signaling in embryonic morphogenesis, cell growth and differentiation. It is thought that RAR-b limits growth of many cell types by regulating gene expression. RAR-beta antibody (mAb) (Clone 8B-10B2) was raised in a Mouse host. It has been validated for use in Immunohistochemistry, Supershift and Western blot, it has been shown to react with Human samples.

Purification: Protein G Chromatography

Immunogen: This RAR-beta antibody was raised against amino acids 413-448 of human RAR-beta.

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: Purified IgG in 70 mM Tris ( pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30 % glycerol and 0.035 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Target Details

Target: RAR-alpha

Alternative Name: RAR-β

Molecular Weight: 50 kDa

NCBI Accession: NP_000956