RAR-alpha (AA 413-448) antibody
Reactivity: Human
IHC, SSA, WB
Host: Mouse
Monoclonal
8B-10B2
unconjugated
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- Target
- RAR-alpha
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Binding Specificity
- AA 413-448
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Reactivity
- Human
-
Host
- Mouse
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Clonality
- Monoclonal
-
Conjugate
- Un-conjugated
- Application
- Immunohistochemistry (IHC), Supershift Assay (SSA), Western Blotting (WB)
- Characteristics
- RAR-b (HAP, NR1B2) is a member of the thyroid-steroid hormone receptor superfamily of nuclear transcriptional regulators. RAR-b localizes to the cytoplasm and to subnuclear compartments. RAR-b binds retinoic acid, the biologically active form of vitamin A which mediates cellular signaling in embryonic morphogenesis, cell growth and differentiation. It is thought that RAR-b limits growth of many cell types by regulating gene expression. RAR-beta antibody (mAb) (Clone 8B-10B2) was raised in a Mouse host. It has been validated for use in Immunohistochemistry, Supershift and Western blot, it has been shown to react with Human samples.
- Purification
- Protein G Chromatography
- Immunogen
- This RAR-beta antibody was raised against amino acids 413-448 of human RAR-beta.
- Clone
- 8B-10B2
- Isotype
- IgG1
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Buffer
- Purified IgG in 70 mM Tris ( pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30 % glycerol and 0.035 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
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- Target
- RAR-alpha
- Alternative Name
- RAR-β
- Molecular Weight
- 50 kDa
- NCBI Accession
- NP_000956
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