TCF4 antibody (N-Term)

Catalog No. ABIN6972845

Product Details anti-TCF4 Antibody

Target: TCF4 (Transcription Factor 4 (TCF4))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TCF4 antibody is un-conjugated

Application: Western Blotting (WB)

Characteristics: TCF4 (Transcription Factor 4) is a transcription factor that binds to the immunoglobulin enchancer Mu-E5/KE5-motif. Involved in the initiation of neuronal differentiation. Activates transcription by binding to the E box (5'-CANNTG-3'). Binds to the E-box present in the somatostatin receptor 2 initiator element (SSTR2-INR) to activate transcription (By similarity). Preferentially binds to either 5'-ACANNTGT-3' or 5'-CCANNTGG-3'. TCF4 antibody (pAb) was raised in a Rabbit host. It has been validated for use in Western blot, it has been shown to react with Human samples.

Purification: Affinity Purified

Immunogen: This antibody was raised against a peptide within the N-terminal region of human TCF4.

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Target Details for TCF4

Target: TCF4 (Transcription Factor 4 (TCF4))

Alternative Name: TCF4 (TCF4 Products)

Synonyms: E2-2 antibody, ITF-2 antibody, ITF2 antibody, PTHS antibody, SEF-2 antibody, SEF2 antibody, SEF2-1 antibody, SEF2-1A antibody, SEF2-1B antibody, TCF-4 antibody, bHLHb19 antibody, 5730422P05Rik antibody, ASP-I2 antibody, E2.2 antibody, ITF-2b antibody, ME2 antibody, MITF-2A antibody, MITF-2B antibody, TFE antibody, Tcf-4 antibody, TCF7L2 antibody, XE2 antibody, Xtcf-4 antibody, Xtcf4 antibody, e2-A antibody, tcf-4 antibody, transcription factor 4 antibody, transcription factor 4 S homeolog antibody, TCF4 antibody, Tcf4 antibody, tcf4 antibody, tcf4.S antibody

Molecular Weight: 85 kDa

NCBI Accession: NP_001230155

Pathways: WNT Signaling, Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, Regulation of Hormone Metabolic Process, Carbohydrate Homeostasis, Stem Cell Maintenance, Protein targeting to Nucleus