PKM2 antibody

Catalog No. ABIN6976349

Product Details anti-PKM2 Antibody

Target: PKM2 (Pyruvate Kinase M2 (PKM2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This PKM2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Specificity: Human PKM2

Cross-Reactivity (Details): does not cross-react with L, R and M1 isotypes

Purification: GammaBind Plus sepharose purified

Purity: > 95 %

Immunogen: Native human pyruvate kinase isoform M2 purified by immunoadsorbant chromatography

Clone: ES2

Isotype: IgG1 kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: PBS

Storage: 4 °C,-20 °C

Storage Comment: Store at 4 °C, short term (1-2 weeks). For long-term storage, aliquot and keep at or below -20° C. Avoid repeated freeze-thaw cycles

Target Details for PKM2

Target: PKM2 (Pyruvate Kinase M2 (PKM2))

Alternative Name: PKM2 (PKM2 Products)

Synonyms: CTHBP antibody, OIP3 antibody, PK3 antibody, PKM2 antibody, TCB antibody, THBP1 antibody, AA414905 antibody, AL024370 antibody, AL024424 antibody, Pk-2 antibody, Pk-3 antibody, Pk3 antibody, Pkm2 antibody, PKM12 antibody, PKM antibody, pyruvate kinase M1/2 antibody, pyruvate kinase, muscle antibody, PKM antibody, Pkm antibody

Background: Pyruvate kinase isoenzyme type M2 (PKM2 or M2-PK) is one of the two isozymes encoded by the human PKM gene. The two isozymes M1 and M2 are alternative splicing products and differ in one of eleven exons. Pyruvate kinase is a critical enzyme in glycolysis as it dephosphorylates phosphoenolpyruvate (PEP) to pyruvate resulting in the net production ATP

Pathways: Warburg Effect