Cyclin C antibody (pSer275) (AbBy Fluor® 350)

Catalog No. ABIN6976518

This anti-Cyclin C antibody is a Rabbit Polyclonal antibody detecting Cyclin C in WB, IF (cc) and IF (p). Suitable for Human, Mouse and Rat.

Quick Overview for Cyclin C antibody (pSer275) (AbBy Fluor® 350) (ABIN6976518)

Target: Cyclin C (CCNC)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cyclin C antibody is conjugated to AbBy Fluor® 350

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-Cyclin C Antibody (AbBy Fluor® 350)

Binding Specificity: pSer275

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Dog,Cow,Sheep,Horse,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated Synthesised phosphopeptide derived from human Cyclin C around the phosphorylation site of Ser275

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for Cyclin C

Target: Cyclin C (CCNC)

Alternative Name: Cyclin C

Background:

Synonyms: Cyclin C (phospho S275), p-Cyclin C (phospho S275), CCNC, CCNC_HUMAN, CycC, Cyclin C, Cyclin-C, CyclinC, hSRB11, OTTHUMP00000016897, SRB11 homolog

Background: The protein encoded by this gene is a member of the cyclin family of proteins. The encoded protein interacts with cyclin-dependent kinase 8 and induces the phophorylation of the carboxy-terminal domain of the large subunit of RNA polymerase II. The level of mRNAs for this gene peaks in the G1 phase of the cell cycle. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Gene ID: 892

UniProt: P24863

Pathways: Cell Division Cycle, Regulation of Lipid Metabolism by PPARalpha