Aryl Hydrocarbon Receptor antibody (AA 241-340) (AbBy Fluor® 488)

Catalog No. ABIN6977877

The AbBy Fluor® 488-conjugated Rabbit Polyclonal anti-Aryl Hydrocarbon Receptor antibody (ABIN6977877) specifically detects Aryl Hydrocarbon Receptor in IF (cc) and IF (p). The antibody is reactive with Human samples.

Quick Overview for Aryl Hydrocarbon Receptor antibody (AA 241-340) (AbBy Fluor® 488) (ABIN6977877)

Target: Aryl Hydrocarbon Receptor (AHR)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Aryl Hydrocarbon Receptor antibody is conjugated to AbBy Fluor® 488

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-Aryl Hydrocarbon Receptor Antibody (AbBy Fluor® 488)

Binding Specificity: AA 241-340

Purpose: AHR Polyclonal Antibody, AbBy Fluor-488 Conjugated

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human AHR

Isotype: IgG

Application Details

Application Notes: IF(IHC-P)(1:50-200), IF(IHC-F)(1:50-200), IF(ICC)(1:50-200)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for Aryl Hydrocarbon Receptor

Target: Aryl Hydrocarbon Receptor (AHR)

Alternative Name: AHR

Background:

Synonyms: Ah receptor, AHR, Aromatic hydrocarbon receptor, Aryl hydrocarbon receptor, Aryl hydrocarbon receptor precursor, BHLHE76, Class E basic helix loop helix protein 76, HGNC:348, AHR_HUMAN.

Background: Ligand-activated transcriptional activator. Binds to the XRE promoter region of genes it activates. Activates the expression of multiple phase I and II xenobiotic chemical metabolizing enzyme genes (such as the CYP1A1 gene). Mediates biochemical and toxic effects of halogenated aromatic hydrocarbons. Involved in cell-cycle regulation. Likely to play an important role in the development and maturation of many tissues.

Gene ID: 196

UniProt: P35869

Pathways: Regulation of Cell Size