NANOS3 antibody (AA 101-173) (AbBy Fluor® 555)

Catalog No. ABIN6978096

The AbBy Fluor® 555-conjugated Rabbit Polyclonal anti-NANOS3 antibody (ABIN6978096) specifically detects NANOS3 in WB, IF (cc) and IF (p). The antibody is reactive with Mouse samples.

Quick Overview for NANOS3 antibody (AA 101-173) (AbBy Fluor® 555) (ABIN6978096)

Target: NANOS3 (Nanos Homolog 3 (NANOS3))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NANOS3 antibody is conjugated to AbBy Fluor® 555

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-NANOS3 Antibody (AbBy Fluor® 555)

Binding Specificity: AA 101-173

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Cow,Sheep,Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Nanos3

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for NANOS3

Target: NANOS3 (Nanos Homolog 3 (NANOS3))

Alternative Name: Nanos3

Background:

Synonyms: NOS3, NANOS1L, Nanos homolog 3, NOS-3, NANOS3

Background: Plays a role in the maintenance of the undifferentiated state of germ cells regulating the spermatogonia cell cycle and inducing a prolonged transit in G1 phase. Affects cell proliferation probably by repressing translation of specific mRNAs. Maintains the germ cell lineage by suppressing both Bax-dependent and -independent apoptotic pathways. Essential in the early stage embryo to protect the migrating primordial germ cells (PGCs) from apoptosis.

Gene ID: 342977

UniProt: P60323

Pathways: ACE Inhibitor Pathway, Regulation of Systemic Arterial Blood Pressure by Hormones, Cellular Response to Molecule of Bacterial Origin, Myometrial Relaxation and Contraction, Signaling Events mediated by VEGFR1 and VEGFR2, Thromboxane A2 Receptor Signaling, VEGFR1 Specific Signals, VEGF Signaling