Caspase 1 p20 antibody (AA 181-280) (AbBy Fluor® 555)

Catalog No. ABIN6978113

The Rabbit Polyclonal anti-Caspase 1 p20 antibody has been validated for WB, FACS, IF (cc) and IF (p). It is suitable to detect Caspase 1 p20 in samples from Human, Mouse and Rat.

Quick Overview for Caspase 1 p20 antibody (AA 181-280) (AbBy Fluor® 555) (ABIN6978113)

Target: Caspase 1 p20

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Caspase 1 p20 antibody is conjugated to AbBy Fluor® 555

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-Caspase 1 p20 Antibody (AbBy Fluor® 555)

Binding Specificity: AA 181-280

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from mouse Caspase-1 p20

Isotype: IgG

Application Details

Application Notes: FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for Caspase 1 p20

Target: Caspase 1 p20

Alternative Name: Caspase-1 p20

Background:

Synonyms: Caspase-1, Casp1, CASP-1, Interleukin-1 beta convertase, IL-1BC, Interleukin-1 beta-converting enzyme, ICE, IL-1 beta-converting enzyme, p45, Casp1, Caspase-1 subunit p20, Il1bc

Background: Thiol protease that cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes. Important for defense against pathogens. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Can also promote apoptosis.

Gene ID: 12362

UniProt: P29452