SPINK5 antibody (AA 21-120) (Biotin)

Catalog No. ABIN6982657

This Rabbit Polyclonal antibody specifically detects SPINK5 in IHC (p) and IHC (fro). It exhibits reactivity toward Human.

Quick Overview for SPINK5 antibody (AA 21-120) (Biotin) (ABIN6982657)

Target: SPINK5 (serine Peptidase Inhibitor, Kazal Type 5 (SPINK5))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SPINK5 antibody is conjugated to Biotin

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-SPINK5 Antibody (Biotin)

Binding Specificity: AA 21-120

Purpose: SPINK5/LEKTI Polyclonal Antibody, Biotin Conjugated

Cross-Reactivity: Human

Predicted Reactivity: Cow,Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SPINK5/LEKTI

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for SPINK5

Target: SPINK5 (serine Peptidase Inhibitor, Kazal Type 5 (SPINK5))

Alternative Name: SPINK5/LEKTI

Background:

Synonyms: Hemofiltrate peptide HF7665, ISK5_HUMAN, LEKTI, Lympho-epithelial Kazal-type-related inhibitor, Lymphoepithelial Kazal type related inhibitor, NETS, NS, Serine peptidase inhibitor Kazal type 5, SPINK5, VAKTI.

Background: This gene encodes a multidomain serine protease inhibitor that contains 15 potential inhibitory domains. The inhibitor may play a role in skin and hair morphogenesis and anti-inflammatory and/or antimicrobial protection of mucous epithelia. Mutations may result in Netherton syndrome, a disorder characterized by ichthyosis, defective cornification, and atopy. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Gene ID: 11005

UniProt: Q9NQ38