KRT8 antibody (Biotin)

Catalog No. ABIN6983084

The Mouse Monoclonal anti-KRT8 antibody has been validated for IHC (p) and IHC (fro). It is suitable to detect KRT8 in samples from Human, Rat and Mouse.

Quick Overview for KRT8 antibody (Biotin) (ABIN6983084)

Target: KRT8 (Keratin 8 (KRT8))

Reactivity: Human, Rat, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This KRT8 antibody is conjugated to Biotin

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: 10A8

Product Details anti-KRT8 Antibody (Biotin)

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein G.

Immunogen: Recombinant human CK8

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for KRT8

Target: KRT8 (Keratin 8 (KRT8))

Alternative Name: Cytokeratin 8

Background:

Synonyms: card2, Cardiac autoantigen 2 120kD, CK 8, CK8, CK-8, ck8, Cyk 8, cyk8, CYKER, Cytokeratin endo A, Cytokeratin-8, Cytokeratin8, DreK8, EndoA, k0, CYK8, k2c8, K2C8_HUMAN, k8, Keratin 8, Keratin type ii cytoskeletal 8, Keratin, type II cytoskeletal 8, Keratin-8, Keratin8, KO, Krt 2.8, Krt 8, krt8, KRT-8, MGC118110, MGC174782, MGC53564, MGC85764, sb:cb186, Type-II keratin Kb8.

Background: This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012].

Gene ID: 3856

UniProt: P05787