IRAK3 antibody (AA 151-250) (Cy3)

Catalog No. ABIN6983416

This Rabbit Polyclonal antibody specifically detects IRAK3 in WB, IF (cc) and IF (p). It exhibits reactivity toward Human.

Quick Overview for IRAK3 antibody (AA 151-250) (Cy3) (ABIN6983416)

Target: IRAK3 (Interleukin-1 Receptor-Associated Kinase 3 (IRAK3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IRAK3 antibody is conjugated to Cy3

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-IRAK3 Antibody (Cy3)

Binding Specificity: AA 151-250

Purpose: IRAKM Polyclonal Antibody, Cy3 Conjugated

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human IRAKM

Isotype: IgG

Application Details

Application Notes: WB(1:300-5000), IF(IHC-P)(1:50-200), IF(IHC-F)(1:50-200), IF(ICC)(1:50-200)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for IRAK3

Target: IRAK3 (Interleukin-1 Receptor-Associated Kinase 3 (IRAK3))

Alternative Name: IRAKM

Background:

Synonyms: ASRT5, IL 1 receptor associated kinase M, IL-1 receptor-associated kinase M, IL1 receptor associated kinase M, Interleukin 1 Receptor Associated Kinase 3, Interleukin 1 Receptor Associated Kinase 3, Interleukin 1 Receptor Associated Kinase M, Interleukin 1 Receptor Associated Kinase M, Interleukin-1 receptor-associated kinase 3, IRAK 3, IRAK 3, IRAK M, IRAK-3, IRAK-M, IRAK3_HUMAN.

Background: Inhibits dissociation of IRAK1 and IRAK4 from the Toll-like receptor signaling complex by either inhibiting the phosphorylation of IRAK1 and IRAK4 or stabilizing the receptor complex.

Gene ID: 11213

UniProt: Q9Y616

Pathways: TLR Signaling, Activation of Innate immune Response, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades