AP3B1 antibody (AA 1-100) (Cy5)

Catalog No. ABIN6984334

This Rabbit Polyclonal antibody specifically detects AP3B1 in WB, IF (cc) and IF (p). It exhibits reactivity toward Human.

Quick Overview for AP3B1 antibody (AA 1-100) (Cy5) (ABIN6984334)

Target: AP3B1 (Adaptor-Related Protein Complex 3, beta 1 Subunit (AP3B1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AP3B1 antibody is conjugated to Cy5

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-AP3B1 Antibody (Cy5)

Binding Specificity: AA 1-100

Purpose: HPS2 Polyclonal Antibody, Cy5 Conjugated

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Rat,Dog,Cow,Sheep,Pig,Horse,Cat,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human HPS2

Isotype: IgG

Application Details

Application Notes: WB(1:300-5000), IF(IHC-P)(1:50-200), IF(IHC-F)(1:50-200), IF(ICC)(1:50-200)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for AP3B1

Target: AP3B1 (Adaptor-Related Protein Complex 3, beta 1 Subunit (AP3B1))

Alternative Name: HPS2

Background:

Synonyms: AP-3 complex subunit beta-1, AP3B1, Adaptor protein complex AP-3 subunit beta-1, Adaptor-related protein complex 3 subunit beta-1, Beta-3A-adaptin, Clathrin assembly protein complex 3 beta-1 large chain, AP3B1, ADTB3A

Background: Subunit of non-clathrin- and clathrin-associated adaptor protein complex 3 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. AP-3 appears to be involved in the sorting of a subset of transmembrane proteins targeted to lysosomes and lysosome-related organelles.

Gene ID: 8546

UniProt: O00203

Pathways: SARS-CoV-2 Protein Interactome