DHRS2 antibody (AA 61-160) (Cy7)
Quick Overview for DHRS2 antibody (AA 61-160) (Cy7) (ABIN6985815)
Target
See all DHRS2 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 61-160
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Cross-Reactivity
- Human, Mouse, Rat
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Purification
- Purified by Protein A.
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Immunogen
- KLH conjugated synthetic peptide derived from human DHRS2
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Isotype
- IgG
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Application Notes
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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Preservative
- ProClin
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Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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Expiry Date
- 12 months
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- DHRS2 (Dehydrogenase/reductase (SDR Family) Member 2 (DHRS2))
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Alternative Name
- DHRS2
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Background
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Synonyms: HEP27, SDR25C1, Dehydrogenase/reductase SDR family member 2, mitochondrial, Dicarbonyl reductase HEP27, Protein D, DHRS2
Background: Displays NADPH-dependent dicarbonyl reductase activity in vitro with 3,4-Hexanedione, 2,3-Heptanedione and 1-Phenyl-1,2-propanedione as substrates. No reductase activity is displayed in vitro with steroids, retinoids and sugars as substrates. Attenuates MDM2-mediated p53/TP53 degradation, leading to p53/TP53 stabilization and increased transcription activity, resulting in the accumulation of MDM2 and CDKN1A/p21.
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Gene ID
- 10202
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UniProt
- Q13268
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Pathways
- C21-Steroid Hormone Metabolic Process
Target
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