ITGB1 antibody (pTyr783) (Cy7)

Catalog No. ABIN6985996

Product Details anti-ITGB1 Antibody (Cy7)

Target: ITGB1 (Integrin beta 1 (ITGB1))

Binding Specificity: pTyr783

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ITGB1 antibody is conjugated to Cy7

Application: Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Human

Predicted Reactivity: Mouse,Rat,Dog,Cow,Sheep,Pig,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthesised phosphopeptide derived from human Integrin beta 1 around the phosphorylation site of Tyr783

Isotype: IgG

Application Details

Application Notes: FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for ITGB1

Target: ITGB1 (Integrin beta 1 (ITGB1))

Alternative Name: Integrin beta 1 (ITGB1 Products)

Background:

Synonyms: Integrin beta 1 (phospho Y783), p-Integrin beta 1 (phospho Y783), beta 1 subunit, CD 29, CD29, CD29 antigen, Fibrinogen Receptor beta subunit, Fibronectin receptor subunit beta, FNRB, Glycoprotein IIa, GP IIa, GPIIA, integrin beta 1 (fibronectin receptor beta polypeptide antigen CD29 includes MDF2 MSK12), Integrin beta-1, Integrin VLA 4 subunit beta, integrin VLA-4 beta subunit, Integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12), ITB1_HUMAN, ITGB 1, ITGB1, MDF2, MSK12, OTTHUMP00000019420, Very Late Activation Protein beta Polypeptide, Very late activation protein, beta polypeptide, VLA BETA, VLA-4 subunit beta, VLA-BETA, VLAB, VLAbeta.

Background: Integrins are heterodimeric proteins made up of alpha and beta subunits. At least 18 alpha and 8 beta subunits have been described in mammals. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metastatic diffusion of tumor cells. This gene encodes a beta subunit. Multiple alternatively spliced transcript variants which encode different protein isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Gene ID: 3688

UniProt: P05556

Pathways: Cell-Cell Junction Organization, Regulation of G-Protein Coupled Receptor Protein Signaling, CXCR4-mediated Signaling Events, Signaling of Hepatocyte Growth Factor Receptor, Integrin Complex, SARS-CoV-2 Protein Interactome