Recombinant CENPC1 antibody (HRP)

Catalog No. ABIN6988076

The Rabbit Monoclonal anti-CENPC1 antibody is suitable to detect CENPC1 in samples from Human. It has been validated for WB, IHC (p) and IHC (fro).

Quick Overview for Recombinant CENPC1 antibody (HRP) (ABIN6988076)

Target: CENPC1 (Centromere Protein C 1 (CENPC1))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This CENPC1 antibody is conjugated to HRP

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-CENPC1 Antibody (HRP)

Purpose: CENPC1 Recombinant Antibody, HRP Conjugated

Cross-Reactivity: Human, Mouse

Purification: Purified by Protein A.

Immunogen: Recombinant human CENPC1 protein

Isotype: IgG

Application Details

Application Notes: WB(1:300-5000), IHC-P(1:200-400), IHC-F(1:100-500)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for CENPC1

Target: CENPC1 (Centromere Protein C 1 (CENPC1))

Alternative Name: CENPC1

Background:

Synonyms: CENP-C 1, CENP-C, CENPC_HUMAN, CENPC1, Centromere autoantigen C, Centromere autoantigen C1, Centromere protein C 1, ICEN7, Interphase centromere complex protein 7, MIF2.

Background: Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation. The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres. CENPC recruits DNA methylation and DNMT3B to both centromeric and pericentromeric satellite repeats and regulates the histone code in these regions.

Gene ID: 1060

UniProt: Q03188