Pleiotrophin antibody

Catalog No. ABIN6988986

The Rabbit Polyclonal anti-Pleiotrophin antibody (ABIN6988986) specifically detects Pleiotrophin in IHC (p), IF (cc), IF (p) and IHC (fro). The antibody is reactive with Human samples.

Quick Overview for Pleiotrophin antibody (ABIN6988986)

Target: Pleiotrophin (PTN)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Pleiotrophin antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-Pleiotrophin Antibody

Purpose: PTN Polyclonal Antibody

Cross-Reactivity: Human

Predicted Reactivity: Mouse,Rat,Cow,Sheep,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PTN

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for Pleiotrophin

Target: Pleiotrophin (PTN)

Alternative Name: PTN

Background:

Synonyms: pleiotrophin, HARP, HBBM, HBGAM, HBGF8, HBNF, HBNF1, Heparin Binding Growth Factor 8, Heparin binding neurite outgrowth promoting factor 1, heparin-binding growth associated molecule, NEGF1, Neurite Growth Promoting Factor 1, OSF-1, osteoblast-specific factor, PTN, PTN_HUMAN.

Background: Secreted growth factor that induces neurite outgrowth and which is mitogenic for fibroblasts, epithelial, and endothelial cells. Binds anaplastic lymphoma kinase (ALK) which induces MAPK pathway activation, an important step in the anti-apoptotic signaling of PTN and regulation of cell proliferation.

Gene ID: 5764

UniProt: P21246

Pathways: RTK Signaling