IDE antibody

Catalog No. ABIN6989431

This Mouse Monoclonal antibody specifically detects IDE in WB. It exhibits reactivity toward Human.

Quick Overview for IDE antibody (ABIN6989431)

Target: IDE (Insulin-Degrading Enzyme (IDE))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This IDE antibody is un-conjugated

Application: Western Blotting (WB)

Clone: 5H4

Product Details anti-IDE Antibody

Cross-Reactivity: Human

Purification: Purified by Protein G.

Immunogen: KLH conjugated synthetic peptide derived from human IDE

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for IDE

Target: IDE (Insulin-Degrading Enzyme (IDE))

Alternative Name: IDE

Background:

Synonyms: BC2, Insulin degrading enzyme, FLJ35968, insulin protease, insulinase, insulysin, Abeta-degrading protease, FLJ35968, Ide, IDE_HUMAN, Insulin-degrading enzyme, OTTHUMP00000020097.

Background: Plays a role in the cellular breakdown of insulin, IAPP, glucagon, bradykinin, kallidin and other peptides, and thereby plays a role in intercellular peptide signaling. Degrades amyloid formed by APP and IAPP. May play a role in the degradation and clearance of naturally secreted amyloid beta-protein by neurons and microglia.

Gene ID: 3416

UniProt: P14735

Pathways: SARS-CoV-2 Protein Interactome