KRT8 antibody

Catalog No. ABIN6989572

This Mouse Monoclonal antibody specifically detects KRT8 in IF, IHC (p), IHC (fro), IF (cc) and IF (p). It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for KRT8 antibody (ABIN6989572)

Target: KRT8 (Keratin 8 (KRT8))

Reactivity: Human, Rat, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This KRT8 antibody is un-conjugated

Application: Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Clone: 10A8

Product Details anti-KRT8 Antibody

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein G.

Immunogen: Recombinant human CK8

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(ICC) 1:50-200
IF()

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for KRT8

Target: KRT8 (Keratin 8 (KRT8))

Alternative Name: Cytokeratin 8

Background:

Synonyms: card2, Cardiac autoantigen 2 120kD, CK 8, CK8, CK-8, ck8, Cyk 8, cyk8, CYKER, Cytokeratin endo A, Cytokeratin-8, Cytokeratin8, DreK8, EndoA, k0, CYK8, k2c8, K2C8_HUMAN, k8, Keratin 8, Keratin type ii cytoskeletal 8, Keratin, type II cytoskeletal 8, Keratin-8, Keratin8, KO, Krt 2.8, Krt 8, krt8, KRT-8, MGC118110, MGC174782, MGC53564, MGC85764, sb:cb186, Type-II keratin Kb8.

Background: This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012].

Gene ID: 3856

UniProt: P05787