CARD9 antibody (C-Term)

Catalog No. ABIN6990390

This anti-CARD9 antibody is a Rabbit Polyclonal antibody detecting CARD9 in WB, ELISA and ICC. Suitable for Human.

Quick Overview for CARD9 antibody (C-Term) (ABIN6990390)

Target: CARD9 (Caspase Recruitment Domain Family, Member 9 (CARD9))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CARD9 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC)

Product Details anti-CARD9 Antibody

Binding Specificity: C-Term

Purification: CARD9 Antibody is affinity chromatography purified via peptide column.

Immunogen: CARD9 antibody was raised against a 16 amino acid peptide near the carboxy terminus of human CARD9. The immunogen is located within the last 50 amino acids of CARD9.

Isotype: IgG

Application Details

Application Notes: CARD9 antibody can be used for detection of CARD9 by Western blot at 2.5 μ,g/mL. A band at approximately 59 kDa can be detected. Antibody can also be used for immunocytochemistry starting at 10 μ,g/mL.

Antibody validated: Western Blot in human samples and Immunocytochemistry in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: CARD9 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: CARD9 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for CARD9

Target: CARD9 (Caspase Recruitment Domain Family, Member 9 (CARD9))

Alternative Name: CARD9

Background: CARD9 Antibody: Apoptosis is related to many diseases and development. Cell death signals are transduced by death domain (DD), death effector domain (DED), and caspase recruitment domain (CARD) containing molecules. CARD containing proteins include some caspases, Apaf-1, CARD4, IAPs, RICK, ARC, RAIDD, BCL-10, and ASC. A novel CARD-containing protein was recently identified and designated CARD9, which interacts with the CARD activation domain of BCL-10. CARD9 associates with BCL-10 and forms a complex within cells. CARD9 induces apoptosis and activates NF-κ,B. CARD9 is an upstream activator of BCL-10 and NF-κ,B signaling.

Molecular Weight: 59 kDa

Gene ID: 64170

UniProt: Q9H257

Pathways: Activation of Innate immune Response