TTC5 antibody (C-Term)

Catalog No. ABIN6990410

The Rabbit Polyclonal anti-TTC5 antibody has been validated for WB, ELISA, IHC (p) and IF. It is suitable to detect TTC5 in samples from Human and Mouse.

Quick Overview for TTC5 antibody (C-Term) (ABIN6990410)

Target: TTC5 (Tetratricopeptide Repeat Domain 5 (TTC5))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TTC5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Product Details anti-TTC5 Antibody

Binding Specificity: C-Term

Purification: TTC5 Antibody is immunoaffinity purified IgG.

Immunogen: TTC5 antibody was raised against a 14 amino acid synthetic peptide from near the carboxy terminus of human TTC5. The immunogen is located within the last 50 amino acids of TTC5.

Isotype: IgG

Application Details

Application Notes: TTC5 antibody can be used for the detection of TTC5 by Western blot at 0.5 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 10 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in mouse samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: TTC5 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: TTC5 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for TTC5

Target: TTC5 (Tetratricopeptide Repeat Domain 5 (TTC5))

Alternative Name: TTC5

Background: TTC5 Antibody: Tetratricopeptide repeat protein 5 (TTC5) is a member of a diverse group of functionally distinct proteins that are characterized by containing one or more tetratricopeptide repeats. Each motif consists of two anti-parallel a-helices such that tandem arrays of TPR motifs generate a right-handed helical structure with an amphipathic channel that may serve to accommodate the complementary region of a target protein. While the exact function of TTC5 remains unclear, it is thought that the TPR motifs serve to mediate protein-protein interactions such as those seen with protein chaperones HSP70 and HSP90 and some proteins involved in cell stress response signaling pathways such as protein phosphatase 5, suggesting that TTC5 may also function via protein-protein interactions mediated by its TPR motifs.

Gene ID: 91875

UniProt: Q8N0Z6

Pathways: Chromatin Binding